Immuno Care

Intensifying… Immunity

Health management and biosecurity are perhaps the most critical aspects of poultry production. Maintaining immune response in the bird is a major challenge as diseases are becoming more complex. The ability of the bird to fight infection and disease is determined by its capacity to respond to invading pathogen. The body protects itself against foreign material such as bacteria & virus through its immune system. Invading organisms trigger the action of lymphocytes.
Humoral Immunity: Specialized cells in the body called B cells produce antibodies against specific pathogens (antigens)
CMI (Cell Mediated Immune Response): Macrophages located in all organs engulf the pathogens which is referred as phagocytocis.
Generally, Humoral Immunity is the main defense against bacteria, while CMI is critical for protection against virus. Even after administration of good vaccine, bird may not develop require protective titer because of its inability to respond ie, immunosuppression due to various reasons.

FACTERS CAUSING IMMUNOSUPPRESSION:

COMPOSITION

Today we need to feed the bird for ‘immunity’ apart from optimal productivity & nutritional supplements play a key role.

VITAMIN E AND SE:

The positive effect of Vit. E on immunity is well established. Vitamin E is an important biological anti-oxidant having synergic action with Selenium. The fast multiplying immune cells need to be protected with higher level of Vit. E and Selenium in the diet.

POLY UNSATURATED FATTY ACIDS(PUFA):

Have received a great deal of attention for their positive effect on chicken immune responses. Higher levels of dietary PUFA promoted the growth of thymus, spleen and bursa and proved to increase immunoglobulin G (IgG) concentration in serum and egg yolk.

ROLE OF HERBAL INGREDIENTS IN IMPROVING IMMUNITY

Amla or Embilica officinalls is a natural efficacious anti-oxidant with the richest natural source of vitamin C. Vitamin C present in amla is more stable compared to synthetic source. In addition it provides several minerals like Chromium, Zinc, Copper, and also Amino Acids like Linolenic acids.
Amla is one of the well known immunomodulator and immunomodulation is due to:

• Anti oxidant property : Protecting the immune cells
• Critical minerals and amino acids : Stimulating activity of immune cells
• Raising the protein levels : Better antibody response

Phyllanthus niruri:Having active principals like phyllanthine, Phyllanthenol, Phyllochrysine, etc is traditionally used to support the biliary and urinary systems, including the gall bladder, Kidney and Liver. It is also found to be an immunomodulator.
Withanla somnifera or Ashwagandha: is commonly known as Guduchi the one which rejuvenates dead cells and used thousands of yeasts as a rejuvenating tonic. The herb is known for its antistress, adaptogenic and immunomodulatory properties. Ashwagandha contains several active constituents including isopelletierine, withanolides,withaferins and acts as immune stimulator probably by:

• Stimulating macrophage activity
• Free radical scavenging effect.

UNIQUE FEATURES:

• Boost the vaccine performance.
• Enhance the birds immunity, specially during viral infections.
• Increase productivity and decrease mortality.
• Balance the stress conditions.

Potentiate Immunity & Combat Heat Stress

RECOMMENDATION FOR DOSE :

Type of bird	Dosage	Reasons
Broilers	5ml/100 birds on 2nd & 3rd week	ND&IBD vaccines are done
Breeders	5ml/100 birds twice a week upto 7weeks and 10ml/100 birds twice a week upto 22 weeks	Most of live and killed vaccines given in prelay
Layers	5ml/100 birds twice a week upto 18 weeks	Most of live and killed vaccines given in prelay

OR

• • 5 ml per 100 birds for 3-5 days
  • 10 ml per 100 birds for 3-5 days during viral infections

• or as directed by the Nutritionist/Veterinarian.

PACKING: 1 Litre HDPE bottle